Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

Figure 1

Electrophoretic analysis of the plasmids carrying the wild type (Wt) and mutant (Mut) alleles of the PSEN-1 gene and original, commercially available plasmids: (1) pEGFP-C1 (4731 bp), (2) pDsRed-N1 (4689 bp) (3) pEGFP-Wt-PSEN1(400) (5075 bp), (4) pEGFP-Mut-PSEN1(400) (5075 bp) (0.5% agarose gel).