Association between the c. 2495 A>G ATP7B Polymorphism and Sporadic Alzheimer's Disease

Table 4

c.2495 A>G ATP7B (exon 10) SNP allele distribution in AD patients and healthy controls and comparison between GG versus AG+AA.

c.2495 A>G ATP7B (exon 10) SNP	AD patients (180)	Controls (151)	P value
Allele A frequency n (%)	127 (35%)	129 (43%)	𝜒^2=3.8;df=1; 𝑃=.05
Allele G frequency n (%)	233 (65%)	173 (57%)
GG n (%)	70 (39%)	44 (29%)	𝑃=.028^∗
AG+AA n (%)	110 (61%)	107 (71%)

Correlation is significant at the .05 level (2-tailed). *The analyses were corrected for the age effect.