Function and Comorbidities of Apolipoprotein E in Alzheimer's Disease

Table 2

APOE polymorphisms in humans and species differences.

ApoE residue; (+signal peptide)	Population prevalence; (%)	112; (130)	158; (176)
Human
APOE2	8	C	C
APOE3	77	C	R
APOE4	15	R	R
Chimp	100	R	R
Gorilla	100	R	R
Orangutan	100	R	R
Mice	100	R	R
Rats	100	R	R

APOE: apolipoprotein E; C: cysteine; R: arginine.