Alzheimer’s Disease Dementia as the Diagnosis Best Supported by the Cerebrospinal Fluid Biomarkers: Difference in Cut-Off Levels from Thai Experience

Figure 3

The receiver operating characteristic curve (ROC) showed mean + SD of the area under the curve (AUC) of CSF beta-amyloid 1-42 for the diagnosis of AD. (AD = 14 and non-AD dementia = 10). AUC = 0.900, SE=0.063, 𝑃=0.001^∗. At the cut-off level 315 pg/mL, it gives the sensitivity of 85.7% and specificity of 90%. At the cut-off level 355 pg/mL, it gives the sensitivity of 92.9% and specificity of 50%. SD: standard deviation, SE: standard errors, ROC: receiver operating characteristic curve, AD: Alzheimer’s disease, ^∗𝑃<0.05.