Research Article

Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action

Figure 1

Open-field assay: effect of GKW on total distance travelled. Wild-type mice, both treated (triangle) and untreated (filled diamond), are less active on the second trial of each day, presumably due to habituation. Untreated Tg2576 mice (open diamond), in contrast, fail to habituate to the surroundings. GKW-treated Tg2576 mice (circles) explore in a manner similar to wild-type mice, with their data overlapping the two wild-type groups. From statistical analysis (ANOVA), for difference between untreated ( ) and GKW-treated ( ) Tg2576 mice; error bars omitted for clarity.
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