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International Journal of Alzheimer’s Disease
Volume 2012 (2012), Article ID 685739, 11 pages
Research Article

Microglial Amyloid- 𝜷 1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer’s Disease

1Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan
2Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan
3Department of Neurology, Mie University, Graduate School of Medicine, Tsu 514-8507, Japan
4Department of Neurology, School of Medicine, Sapporo Medical University, S1W16, Chuo-ku, Sapporo 060-8543, Japan

Received 30 November 2011; Accepted 24 February 2012

Academic Editor: Akio Suzumura

Copyright © 2012 Kazuyuki Takata et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [4 citations]

The following is the list of published articles that have cited the current article.

  • Stephanie Busch, Liang Wu, Yuxi Feng, Norbert Gretz, Sigrid Hoffmann, and Hans-Peter Hammes, “Alzheimer's Disease and Retinal Neurodegeneration Share a Consistent Stress Response of the Neurovascular Unit,” Cellular Physiology And Biochemistry, vol. 30, no. 6, pp. 1436–1443, 2012. View at Publisher · View at Google Scholar
  • Antero Salminen, Kai Kaarniranta, Anu Kauppinen, Johanna Ojala, Annakaisa Haapasalo, Hilkka Soininen, and Mikko Hiltunen, “Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome,” Progress in Neurobiology, 2013. View at Publisher · View at Google Scholar
  • Jessica F. Jordão, Emmanuel Thévenot, Kelly Markham-Coultes, Tiffany Scarcelli, Ying-Qi Weng, Kristiana Xhima, Meaghan O'Reilly, Yuexi Huang, JoAnne McLaurin, Kullervo Hynynen, and Isabelle Aubert, “Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound,” Experimental Neurology, 2013. View at Publisher · View at Google Scholar
  • Domenica Musumeci, Giovanni N. Roviello, and Daniela Montesarchio, “An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies,” Pharmacology & Therapeutics, 2013. View at Publisher · View at Google Scholar