685739.fig.006a
(a)
685739.fig.006b
(b)
685739.fig.006c
(c)
685739.fig.006d
(d)
685739.fig.006e
(e)
685739.fig.006f
(f)
Figure 6: Laser confocal microscopic study on the accumulation of HMGB1 and microglia on A 40 plaques in human AD brains. (a–c) Free-floating human AD brain sections were incubated with the anti-A 40 specific antibody ((a) red) and anti-HLA-DR antibody ((b) for microglial staining, green). The merged image is indicated in (c). (d–f) Free-floating human AD brain sections were incubated with the anti-A 40 specific antibody ((a); red) and anti-HMGB1 antibody ((b); green). The merged image is indicated in (f). Scale bar in (a) equals 50 μm for all panels.