Quantitative EEG Markers in Mild Cognitive Impairment: Degenerative versus Vascular Brain Impairment

Table 3

Mean values ± standard deviation of sociodemographic characteristics, MMSE scores, white matter hyperintensities, and hippocampal and amygdalar volume measurements. Hippocampal and amygdalar volumes refer tothe whole amygdalohippocampal complex (AHC) and are singularly considered (individual). The 𝑡-test refers to AHC versus individual volume in each group.

	MCI cohort	Group 1	Group 2	Group 3	𝑃 value (ANOVA)
Number of subjects (f/m)	79 (42/37)	27 (14/13)	27 (15/12)	25 (13/12)
Age (years)	69.2±2.3	66.8±6.8	69.4±8.7	71.5±6.9	0.1
Education (years)	7.7±0.8	8.3±4.5	6.7±3.1	8.2±4.6	0.2
MMSE	27.1±0.4	27.5±1.5	27.4±1.5	26.6±1.8	0.1
Total AHC volume	6965.3±1248.8	8151.2±436.4	7082.7±266.9	5661.8±720.4	0.00001
AHC-hippocampal volume (mm^3)	4891.7±902.6	5771.6±361.1	4935.6±380.9	3967.9±650.3	0.00001
AHC-amygdalar volume (mm^3)	2073.5±348.7	2379.6±321.3	2147.1±301.3	1693.9±288.5	0.0001
Individual hippocampal volume (mm^3)	4889.8±962.4	5809.6±314.2	4969.4±257.6	3890.1±551.4	0.00001
Individual amygdalar volume (mm^3)	2071.7±446.4	2514.4±259.5	2079.2±122.8	1621.6±185.2	0.0001
White matter hyperintensities (mm^3)	3.8±0.5	3.2±2.8	4.2±3.8	4.1±3.6	0.7