Table 1: Tau constructs available in Drosophila.

ConstructsTypeOrigin

Drosophila  constructs
 UAS-dTauWild-typeMershin et al. 2004 [32]
 UASp-dTauA:mGFP6FusionDoerflinger et al. 2003 [33]
 UAS-dTau:1D4Tagged formFeuillette et al. 2010 [34]

Bovine constructs
 UAS-bTauWild-typeIto et al. 1997 [18]
:GFPFusionMicklem et al. 1997 [35]
 UAS-bTau:GFPFusionMurray et al. 1998 [19]
 UAS-bTau:lacZFusionCallahan and Thomas 1994 [20]

Human 0N3R construct
 UAS-hTauWilliams et al. 2000 [21]

Human 2N4R constructs
 gl-hTauWild-typeJackson et al. 2002 [7]
 gl-hTauP301LFTDP17 mutationKarsten et al. 2006 [22]
 UAS-hTauChatterjee et al. 2009 [23]
 gl-hTauS2A (S262A/S356A)Phospho-deficientChatterjee et al. 2009 [23]
 UAS-hTauS2A (S262A/S356A)Phospho-deficientChatterjee et al. 2009 [23]
 gl-hTauS11A
  (S46A/T50A/S199A/S202A/
  S205A/T212A/ S214A/T231A/Phospho-deficientChatterjee et al. 2009 [23]
  S235A/S396A/S404A)
 UAS-hTauS11A
  (S46A/T50A/S199A/S202A/
  S205A/T212A/S214A/T231A/Phospho-deficientChatterjee et al. 2009 [23]
   S235A/S396A/S404A)
 UAS-hTau:FLAGTagged formKosmidis et al. 2010 [24]
 UAS-hTauSTA:FLAG  (S238A/T245A)Tagged form Phospho-deficientKosmidis et al. 2010 [24]

Human 0N4R constructs
 UAS-hTauWild-typeWittmann et al. 2001 [6]
 UAS-hTauV337MFTDP17 mutationWittmann et al. 2001 [6]
 UAS-hTauR406WFTDP17 mutationWittmann et al. 2001 [6]
 UAS-hTauR406W  S2A (S262A/S356A)FTDP17 mutation Phospho-deficientNishimura et al. 2004 [25]
 UAS-hTauR406W  S202AFTDP17 mutation Phospho-deficientNishimura et al. 2004 [25]
 UAS-hTauT111A/T153APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauT175A/T181APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauT199A/T217APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauS202A/S205APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauT212APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauS214APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauT231A/S235APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauS262APhospho-deficientIijima-Ando et al. 2010 [28]
 UAS-hTauS396A/S404APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauS422APhospho-deficientSteinhilb et al. 2007 MBC [26]
 UAS-hTauAP5
  (S202A/S205A/T212A/Phospho-deficientSteinhilb et al. 2007 MBC [26]
  T231A/S235A)
 UAS-hTauAP
  (T111A/T153A/T175A/T181A/
   S199A/S202A/S205A/T212A/Phospho-deficientSteinhilb et al. 2007 JNR [26]
   S214A/T217A/T231A/S235A/
   S396A/S404A/S422A)
 UAS-hTauE14
   (T111E/T153E/T175E/T181E/
   S199E/S202E/S205E/ T212E/PhosphomimeticKhurana et al. 2006 [29]
   T217E/T231E/S235E/S396E/
   S404E/S422E)
 UAS-hTauK44Q/R230QCalpain-resistantReinecke et al. 2011 [30]
Calpain 17kDA proteolytic fragmentReinecke et al. 2011 [30]
C-terminally truncated TauKhurana et al. 2010 [31]