Table 2: Readouts of Tau toxicity in Drosophila.

Organ/Tissue/Cells Phenotypes Promoters/Drivers Eye Roughness GMR Photoreceptor cell viability Gl Sev Notum Loss of bristles Eq Nervous system Lethality Elav Shortened lifespan Appl Brain vacuolisation Repo TUNEL positive cells Gl Activated caspase3 positive cells C472 Loss of olfactory Learning and memory C772 Motor neurons Axonal transport defects D42 Locomotor deficits OK6 “juvenile” phenotype: loss of wing Elav expansion and cuticle tanning Burs12 Appl