Table 2: Readouts of Tau toxicity in Drosophila.

Organ/Tissue/CellsPhenotypesPromoters/Drivers

EyeRoughnessGMR
Photoreceptor cell viabilityGl
Sev

NotumLoss of bristlesEq

Nervous systemLethalityElav
Shortened lifespanAppl
Brain vacuolisationRepo
TUNEL positive cellsGl
Activated caspase3 positive cellsC472
Loss of olfactory Learning and memoryC772

Motor neuronsAxonal transport defectsD42
Locomotor deficitsOK6
“juvenile” phenotype: loss of wingElav
expansion and cuticle tanningBurs12
Appl