A Unifying Hypothesis for Familial and Sporadic Alzheimer's Disease
Figure 4
Simulation results for model with high aggregation rates and increased Aβ clearance at different time points. Each graph shows the mean of 100 simulations. The clearance rate of Aβ was increased at the following time points: (a) Day 0, (b) Day 2, (c) Day 4, (d) Day 6, (e) Day 8, (f) No intervention. p53 bound to GSK3β (GSK3b_p53), damaged DNA (damDNA), ROS, tau tangles and Aβ monomers, oligomers and plaques, are shown.
