Research Article

Cumulative Effect of Depression on Dementia Risk

Table 3

Final regression model for dementia prevalence at baseline.

VariableAll dementiaDementia due to AD
OR (95% CI) valueOR (95% CI) value

Sex (female)1.45 (0.90–2.35)NS1.65 (0.93–2.92)NS
Age2.40 (2.02–2.85)<0.0011.20 (1.16–1.24)<0.001
Education
 Illiterate3.06 (1.21–7.77)<0.052.38 (0.79–7.15)NS
 Can read and write1.38 (0.54–3.53)NS1.13 (0.37–3.45)NS
 Primary school1.63 (0.60–2.41)NS1.47 (0.47–4.66)NS
 ≥secondary school1 (reference)1 (reference)
Depression
 nD1 (reference)1 (reference)
 pD1.52 (0.54–4.31)NS0.45 (0.06–3.40)NS
 prD1.84 (1.01–3.35)<0.051.98 (0.98–3.99)NS
 prpD2.73 (1.08–6.87)<0.053.98 (1.48–10.71)<0.005
Hypertension0.63 (0.41–0.96)<0.050.64 (0.39–1.06)NS
Stroke4.11 (2.14–7.88)<0.0010.20 (0.02–1.60)NS

Fully adjusted model. The variables that did not enter or did not remain in the model were diabetes, heart disease, and hypercholesterolemia.
AD: Alzheimer's disease (without vascular component); nD: never depression; pD: past depression; prD: present depression; prpD: present and past depression; NS: statistically not significant ( ).