Review Article

Cholesterol and Copper Affect Learning and Memory in the Rabbit

Figure 4

Structural MRI scan of a rabbit that received normal chow and distilled drinking water (a), normal chow and 0.12 ppm copper added to the distilled drinking water (b), 2% cholesterol and distilled drinking water (c), or 2% cholesterol and copper added to the distilled drinking water (d). The inset shows the area around the third ventricle in each rabbit and the red shading illustrates the significantly larger area of the third ventricle for cholesterol-fed rabbits ((c) and (d)) compared to the chow-fed control rabbits ((a) and (b)). The data show significant increases in the area of the third ventricle as a function of being fed cholesterol. Data are modified from [72].
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(a)
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(b)
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(c)
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(d)