Anticholinesterase and Antioxidative Properties of Aqueous Extract of Cola acuminata Seed In Vitro

Table 1

IC₅₀ values for the acetylcholinesterase and butyrylcholinesterase inhibitory activities; inhibition of FeSO₄, SNP, and quinolinic acid induced MDA production in rats brain homogenates in vitro; and scavenging ability as well as Fe²⁺ chelating ability.

Parameters	Values (units)
Acetylcholinesterase	14.6 ± 1.04 (g/mL)
Butyrylcholinesterase	96.2 ± 7.07 (g/mL)
FeSO4 induced	0.16 ± 0.12 (mg/mL)
SNP induced	0.76 ± 0.10 (mg/mL)
QA induced	0.51 ± 0.04 (mg/mL)
	2.10 ± 0.08 (mg/mL)
	0.97 ± 0.03 (mg/mL)
Fe chelation	1.09 ± 0.14 (mg/mL)

Values represent means ± standard deviation of triplicate readings ( = 3).