Altered Proteolysis in Fibroblasts of Alzheimer Patients with Predictive Implications for Subjects at Risk of Disease

<table>Combined APOE/TK-ab tests in 6 families of probable AD patients. Combined results of the clinical diagnosis and genetic and biochemical tests in members of 6 representative families, each with a probable AD patient (square symbol) and 2 to 3 relatives (R). TK-ab positivity corresponded to closed symbols. APOE genotypes are indicated inside symbols.</table>

International Journal of Alzheimer’s Disease

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Figure 3: Altered Proteolysis in Fibroblasts of Alzheimer Patients with Predictive Implications for Subjects at Risk of Disease 