Nanoscale Extracellular Vesicle Analysis in Alzheimer’s Disease Diagnosis and Therapy

Figure 1

Three-dimensional nsEV phenotyping Cartesian coordinate system. The -axis defines nsEV method of nsEV isolation dimension; anti-CD9 IP and anti-CD81 IP are denoted as two representative -axis points. The -axis defines nsEV cell type origin dimension; intestinal epithelium and neuron are denoted as two representative -axis points. The -axis defines biomarker abundance dimension. The -axis units will vary depending upon the method used to quantify biomarker abundance(s); no representative -axis points are denoted in this figure.