Nanoscale Extracellular Vesicle Analysis in Alzheimer’s Disease Diagnosis and Therapy

Figure 3

ExoScreen luminescent nsEV quantification assay data for various combinations of AlphaLISA donor and acceptor beads. Data show that ExoScreen allows quantification of neuronal exosomes in plasma. The -axis denotes AlphaLISA luminescence units. The -axis denotes microliters of plasma added to assay. CD9/CD9 donor/acceptor AlphaLISA luminescence data points represent averages of two measurements; values varied by less than 10% across duplicate measurements. Data points for CD56/CD9 and negative control Ab/negative control Ab bead combinations correspond to single measurements.