Research Article

Comparative Neuroprotective Effects of Dietary Curcumin and Solid Lipid Curcumin Particles in Cultured Mouse Neuroblastoma Cells after Exposure to Aβ42

Figure 1

SLCP has greater cellular permeability than dietary Cur. (a) Schematic diagram showing the formulation of SLCP, indicating that Cur is coated with solid lipid core of a lipid bilayer. (b) Mouse embryonic primary hippocampal neurons (7 days old) were treated with Cur and SLCP in different time points, with SLCP showing greater permeability than dietary Cur after 2 and 4 h incubation. N2a cells were treated with SLCP (1 μM) up to 24 h and maximum permeability was observed after 1 h with no significant change of permeability, even up to 24 h of incubation. Scale bar indicates 100 μm and is applicable to all images.
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