Research Article

Effects of Chlorophyll-Derived Efflux Pump Inhibitor Pheophorbide a and Pyropheophorbide a on Growth and Macrolide Antibiotic Resistance of Indicator and Anaerobic Swine Manure Bacteria

Table 1

Culture counts of anaerobic bacteria from stored swine manure.

Viable counts: swine slurry medium*
+H2O/EtOH+erythromycin+tylosin

−pyp1.26 × 109(±0.13 × 109)1.01 × 109(±0.30 × 109)1.07 × 109(±0.15 × 109)
+pyp8.99 × 108(±1.69 × 108)8.90 × 108(±2.66 × 108)1.09 × 109(±0.22 × 109)

 *(CFU mL−1) on swine slurry medium supplemented with pyropheophorbide a (pyp, 10 µg mL−1) alone and in combination with erythromycin, tylosin (10 µg mL−1, individually) or water and ethanol (H2O/EtOH, control). Values are averages and standard deviations from three repeated experiments with duplicates.