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International Journal of Breast Cancer
Volume 2011 (2011), Article ID 235926, 8 pages
http://dx.doi.org/10.4061/2011/235926
Research Article

Electric Field Analysis of Breast Tumor Cells

1Anna University, Chennai 600 025, India
2Purdue University, West Lafayette, IN 47907, USA

Received 6 June 2011; Revised 30 August 2011; Accepted 30 August 2011

Academic Editor: E. Y. K. Ng

Copyright © 2011 V. Gowri Sree et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this.