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International Journal of Breast Cancer
Volume 2011 (2011), Article ID 246265, 5 pages
http://dx.doi.org/10.4061/2011/246265
Research Article

Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI

1Department of Radiation Oncology, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
2Department of Biostatistics, College of Public Health, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA

Received 30 December 2010; Accepted 13 February 2011

Academic Editor: Mo Keshtgar

Copyright © 2011 Geraldine Jacobson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Accurate lumpectomy cavity definition is critical in breast treatment planning. We compared contouring lumpectomy cavity volume and cavity visualization score (CVS) with CT versus 3T MRI. 29 patients were imaged with CT and 3T MRI. Seven additional boost planning sets were obtained for 36 image sets total. Three observers contoured the lumpectomy cavity on all images, assigning a cavity visualization score (CVS ) of 1 to 5. Measures of consistency and agreement for CT volumes were 98.84% and 98.62%, for T1 MRI were 95.65% and 95.55%, and for T2 MRI were 97.63% and 97.71%. The mean CT, T1 MRI, and T2 MRI CVS scores were 3.28, 3.38, and 4.32, respectively. There was a highly significant difference between CT and T2 scores ( 𝑃 < . 0 0 0 0 1 ) and between T1 and T2 scores ( 𝑃 < . 0 0 0 0 1 ). Interobserver consistency and agreement regarding volumes were high for all three modalities with T2 MRI CVS the highest. MRI may contribute to target definition in selected patients.