Imaging-Assisted Large-Format Breast Pathology: Program Rationale and Development in a Nonprofit Health System in the United States

Figure 7

Large-format section of a lumpectomy specimen with circumferential surgical margin (broken line). Biopsy cavity is centrally located (solid red). Grade 2 DCIS (solid green) extends 15 mm from the cavity to within 9 mm of true surgical margin. Arrow marks migration of India ink into specimen to within 1 mm from DCIS. A conventional histologic section taken in this area could misrepresent the margin distance as 1 mm. This pitfall is easily avoided on the large-format slide. Scale: small divisions = 1.0 mm (H&E).