Evaluating Surveillance Breast Imaging and Biopsy in Older Breast Cancer Survivors
Table 5
Multivariate poisson GEE models* for breast events.
Mammogram
US/MRI
Biopsy
Number of breast events
Characteristic
IRR
95% CI
-value
IRR
95% CI
-value
IRR
95% CI
-value
IRR
95% CI
-value
Age group
65–69
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
70–74
1.01
(0.97, 1.05)
0.76
0.98
(0.68, 1.40)
0.90
1.05
(0.80, 1.39)
0.72
0.98
(0.91, 1.05)
0.55
75–80
0.98
(0.93, 1.02)
0.31
0.65
(0.41, 1.02)
0.06
0.66
(0.45, 0.96)
0.03
0.90
(0.83, 0.97)
0.01
80+
0.89
(0.83, 0.95)
0.001
0.73
(0.45, 1.20)
0.21
0.54
(0.36, 0.83)
0.005
0.82
(0.75, 0.90)
0.001
Stage at diagnosis
I
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
DCIS
1.00
(0.95, 1.04)
0.92
0.97
(0.67, 1.42)
0.88
1.04
(0.76, 1.40)
0.82
1.00
(0.94, 1.07)
0.88
IIA
0.93
(0.89, 0.99)
0.01
0.62
(0.40, 0.97)
0.04
0.66
(0.46, 0.94)
0.51
0.85
(0.79, 0.92)
0.001
IIB
0.87
(0.79, 0.97)
0.01
0.82
(0.44, 1.52)
0.52
1.15
(0.76, 1.73)
0.51
0.81
(0.71, 0.94)
0.01
III
0.86
(0.71, 1.01)
0.06
0.62
(0.24, 1.61)
0.32
0.73
(0.34, 1.59)
0.44
0.65
(0.52, 0.81)
0.001
Primary therapy
Mastectomy
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
Breast conserving surgery with radiation
1.09
(1.06, 1.12)
0.001
1.11
(0.76, 1.64)
0.59
1.12
(0.83, 1.51)
0.46
1.22
(1.14, 1.30)
0.001
Breast conserving surgery
1.00
(0.94, 1.07)
0.90
1.68
(1.06, 2.66)
0.03
0.95
(0.59, 1.50)
0.82
1.19
(1.08, 1.31)
0.001
Unknown/Other
0.77
(0.68, 0.87)
0.001
1.07
(0.53, 2.18)
0.85
0.63
(0.34, 1.16)
0.14
0.81
(0.70, 0.94)
0.01
Family history
No
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
Yes
1.02
(0.98, 1.06)
0.22
0.88
(0.63, 1.23)
0.45
0.97
(0.75, 1.27)
0.86
1.03
(0.97, 1.09)
0.38
Unknown
0.96
(0.75, 1.24)
0.78
NA
NA
NA
0.78
(0.12, 4.92)
0.80
0.81
(0.63, 1.03)
0.09
Comorbidities
0
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1
0.97
(0.93, 1.02)
0.24
0.93
(0.65, 1.34)
0.72
1.18
(0.88, 1.58)
0.27
0.97
(0.90, 1.05)
0.48
2+
0.97
(0.92, 1.03)
0.34
1.02
(0.64, 1.62)
0.95
1.09
(0.73, 1.62)
0.68
0.92
(0.84, 1.00)
0.06
Education
Less than high school
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
1.00
(—, —)
High school/ged
1.04
(0.97, 1.11)
0.24
0.87
(0.50, 1.52)
0.63
1.03
(0.67, 1.61)
0.86
1.06
(0.95, 1.17)
0.30
Some college
1.00
(0.93, 1.07)
0.95
1.02
(0.58, 1.82)
0.94
1.10
(0.69, 1.74)
0.69
1.00
(0.90, 1.12)
0.88
College or post graduate
1.02
(0.95, 1.10)
0.52
1.01
(0.57, 1.80)
0.96
0.97
(0.60, 1.55)
0.90
1.03
(0.92, 1.15)
0.60
Unknown
1.01
(0.93, 1.11)
0.74
0.91
(0.44, 1.89)
0.80
1.42
(0.85, 2.36)
0.18
1.02
(0.89, 1.16)
0.81
*Adjusted for all characteristics listed in the table and diagnosis year, number of primary or specialty care visits, and proportion of specialty care visits. IRR: incidence rate ratio; 95% CI: 95% confidence interval.
