The Role of Large-Format Histopathology in Assessing Subgross Morphological Prognostic Parameters: A Single Institution Report of 1000 Consecutive Breast Cancer Cases
Figure 1
The basic breast cancer growth patterns. (a) Unifocal in situ carcinoma: the tumor involves neighboring terminal ductal-lobular units. (b) Multifocal in situ carcinoma: the tumor involves distant terminal ductal-lobular units. (c) Diffuse in situ carcinoma: the tumor involves large ducts and many terminal ductal-lobular units. (d) Unifocal invasive carcinoma: a single well-delineated invasive focus. (e) Multifocal invasive carcinoma: several well-delineated invasive foci in the same specimen. (f) Diffuse invasive carcinoma: poorly delineated, spider’s web-like structure. All the malignant lesions are encircled.
