Metastatic Breast Cancer to the Gastrointestinal Tract: Report of Five Cases and Review of the Literature

Table 1

Clinical characteristics of patients with breast cancer and GI tract involvement.

Pts/age	Breast cancer onset	Histology	TNM/G; (breast cancer onset)	ER/PgR (%)	Ki-67; (%)	c erbB2	Treatment of primary tumor	Date and site of GI involvement	Treatment of GI involvement	Current; status
I/47	March 1985	DIC	PT2N0M0/n.a.	>95/0	10	Negative	Surgery	December 2007/jejunum	Surgery,; CT, ET	Alive; June 2012
II/40	May 2008	Signet ring cells	CTxN1M1/2	90/35	15	Negative	CT, ET	May 2008/rectum	CT, ET, RT	Alive; June 2012
III/53	1987	DIC	n.a./n.a.	>80/>80	10	Negative	Surgery	March 2008/stomach	CT	Death; August 2008
IV/57	January 2006	LIC	PT2N3aM1/n.a.	80/85	10	Negative	Surgery, CT, ET	November 2008/stomach	CT	Death; May 2009
V/63	1998	LIC	pT2N2M0/n.a.	50/0	10	Negative	Surgery, CT, ET	October 2010/stomach	ET	Alive; June 2012

CT: chemotherapy; ET: endocrine therapy; RT: radiotherapy; DIC: ductal infiltrating carcinoma; LIC: lobular infiltrating carcinoma, n.a.: not assessable.