Review Article
Metastatic Breast Cancer to the Gastrointestinal Tract: Report of Five Cases and Review of the Literature
Table 1
Clinical characteristics of patients with breast cancer and GI tract involvement.
| Pts/age | Breast cancer onset | Histology | TNM/G (breast cancer onset) | ER/PgR (%) | Ki-67 (%) | c erbB2 | Treatment of primary tumor | Date and site of GI involvement | Treatment of GI involvement | Current status |
| I/47 | March 1985 | DIC | PT2N0M0/n.a. | >95/0 | 10 | Negative | Surgery | December 2007/jejunum | Surgery, CT, ET | Alive June 2012 | II/40 | May 2008 | Signet ring cells | CTxN1M1/2 | 90/35 | 15 | Negative | CT, ET | May 2008/rectum | CT, ET, RT | Alive June 2012 | III/53 | 1987 | DIC | n.a./n.a. | >80/>80 | 10 | Negative | Surgery | March 2008/stomach | CT | Death August 2008 | IV/57 | January 2006 | LIC | PT2N3aM1/n.a. | 80/85 | 10 | Negative | Surgery, CT, ET | November 2008/stomach | CT | Death May 2009 | V/63 | 1998 | LIC | pT2N2M0/n.a. | 50/0 | 10 | Negative | Surgery, CT, ET | October 2010/stomach | ET | Alive June 2012 |
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CT: chemotherapy; ET: endocrine therapy; RT: radiotherapy; DIC: ductal infiltrating carcinoma; LIC: lobular infiltrating carcinoma, n.a.: not assessable.
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