The Ongoing Revolution in Breast Imaging Calls for a Similar Revolution in Breast Pathology
Figure 2
(a) A stepwedge expressing the discrepancy between the low-resolution mammographic image and high-resolution histologic image. The mammogram shows calcifications localized in a well-defined structure of the breast (ducts), while the interpretation of the histopathologic finding emphasizes the cellular details not seen by the radiologists. There is a communication gap since the radiologist expects a detailed description of tissue structure, in addition to the description of cellular features. (b) The communication gap can be overcome with the help of subgross (3D) histology. In this case the location of fragmented casting type calcifications and the intraductal pathologic process producing them can be clearly seen on the subgross (3D) image, providing excellent radiologic-pathologic correlation.
