Research Article

Age at Diagnosis and Breast Cancer Survival in Iran

Table 2

Tumour characteristics of breast cancer patients in Iran diagnosed in the period of 1999–2001.

Age at diagnosis Total ( ) value
<35
35–49
50–64
65+

Tumour size (cm)
 <2 cm
 2–5 cm
 >5 cm
 Missing
32 (14.8)
121 (56.0)
37 (17.1)
26 (12.1)
129 (17.3)
404 (54.2)
137 (18.4)
75 (10.1)
60 (14.5)
232 (55.9)
87 (21.0)
36 (8.6)
16 (12.9)
64 (15.6)
36 (29.0)
8 (6.5)
237 (15.8)
821 (54.7)
297 (19.8)
145 (9.7)
0.04*

Lymph node involvement
 0 node
 1–3 nodes
 4–9 nodes
 10+ nodes
 Missing
46 (21.3)
50 (23.2)
80 (37.0)
15 (6.9)
25 (11.6)
135 (18.1)
169 (22.7)
320 (43.0)
33 (4.4)
88 (11.8)
67 (16.2)
106 (25.6)
167 (40.2)
35 (8.4)
40 (9.6)
21 (16.9)
20 (16.1)
45 (36.3)
29 (23.4)
9 (7.3)
269 (17.9)
345 (23.0)
612 (40.8)
112 (7.5)
162 (10.8)
0.00*

Distant metastases
 No
 Yes
 Missing
160 (74.1)
27 (12.5)
29 (13.4)
551 (74.0)
104 (14.0)
90 (12.0)
311 (75.0)
61 (14.7)
43 (10.3)
75 (60.5)
32 (25.8)
17 (13.7)
1097 (73.2)
224 (14.9)
179 (11.9)
0.01*

Grade
 Grade 1
 Grade 2
 Grade 3
 Missing
14 (6.5)
85 (39.4)
26 (12.0)
91 (42.1)
44 (5.9)
303 (40.7)
60 (8.0)
338 (45.4)
18 (4.3)
161 (38.8)
46 (11.1)
190 (45.8)
5 (4.0)
21 (16.9)
37 (29.9)
61 (49.2)
81 (5.4)
570 (38.0)
169 (11.3)
680 (45.3)
0.00*

Estrogens receptor
 Negative
 Positive
 Unknown/not done
61 (28.2)
119 (55.1)
36 (16.7)
185 (24.8)
420 (56.4)
140 (18.8)
89 (21.4)
225 (54.2)
101 (24.3)
30 (24.2)
73 (58.9)
21 (16.9)
365 (24%)
837 (56%)
298 (20%)
0.14

Progesterone receptor
 Negative
 Positive
 Unknown/not done
53 (24.5)
128 (59.3)
35 (16.2)
226 (30.3)
381 (51.1)
138 (18.5)
121 (29.2)
188 (45.3)
106 (25.5)
37 (29.8)
66 (53.2)
21 (16.9)
437 (29%)
763 (51%)
300 (20%)
0.00*

Her-2 expression
 Positive
 Negative
 Unknown/not done
71 (32.9)
32 (14.8)
113 (52.3)
190 (25.5)
118 (15.8)
437 (58.7)
95 (22.9)
73 (17.6)
247 (59.5)
31 (25.0)
22 (17.7)
71 (57.3)
245 (16.3)
387 (25.8)
868 (57.9)
0.00*

Tumour subtype
 Ductal
 Lobular
 Medullary
 Other
190 (88.0)
9 (4.2)
16 (7.4)
1 (0.5)
658 (88.3)
32 (4.3)
43 (5.8)
12 (1.6)
368 (88.7)
27 (6.5)
16 (3.9)
4 (1.0)
112 (90.3)
8 (6.5)
3 (2.4)
1 (0.8)
1328 (87.0)
76 (4.9)
78 (4.5)
18 (1.2)
0.20

*Significant at α = 0.05.