Age at Diagnosis and Breast Cancer Survival in Iran
Table 4
Relative excess risk of breast cancer death in Iranian women diagnosed in 1999–2001.
Univariate
Multivariate
Factors
RER
95% CI
Adjusted¥ RER (95% CI) (before imputation)
Adjusted RER (after imputation)
(95% CI)
Age at presentation
<35
1
Reference
1
1
35–49
1.0
(0.64–1.68)
1.2
(0.46–3.13)
1.1
(0.66–1.78)
50–64
1.0
(0.56–1.92)
1.7
(0.62–5.03)
1.1
(0.61–1.92)
65+
—
1.1
(0.12–10.23)
0.5
(0.11–2.65)
TNM-stage
I
1
Reference
1
1
II
2.0
(0.50–8.04)
2.1
(0.35–29.78)
1.2
(0.42–3.74)
III
2.4
(0.60–10.23)
3.2
(0.21–22.32)
1.3
(0.41–4.02)
IV
4.3
(1.10–17.63)*
6.5
(0.64–64.83)
1.7
(0.52–5.22)
Grade (imputed)
(Nonimputed)
(680 imputed values)
Grade 1
1
Reference
1
1
Grade 2
2.2
(0.66–7.31)
3.8
(0.47– 30.62)
2.1
(0.67–6.45)
Grade 3
7.0
(2.10–23.10)*
6.6
(0.49–88.39)
8.4
(2.63–27.16)*
Estrogens receptor
Negative
1
Reference
1
1
Positive/unknown
0.8
(0.50–1.18)
0.9
(0.38–2.23)
0.7
(0.38–1.12)
Progesterone receptor
Negative
1
Reference
1
1
Positive/unknown
0.8
(0.55–1.28)
0.7
(0.30–1.64)
1.1
(0.65–1.85)
Her-2 expression (imputed)
(Nonimputed)
(868 imputed values)
Positive
1
Reference
1
1
Negative
0.5
(1.30–2.74)*
0.5
(0.24–1.00)
0.4
(0.25–0.57)*
¥Adjusted for all other variables in this table (full model) and place of residency. Relative survival from patients aged 65+ is >1, corresponding to a negative excess hazard in our model, but the model does not allow for negative excess hazards.
*Statistically significant at α = 0.05.
