3D Pathology Volumetric Technique: A Method for Calculating Breast Tumour Volume from Whole-Mount Serial Section Images

Figure 2

Selected serial whole-mount sections (Case A) in IDC NOS, diffuse pattern. The orientation is consistent for all of the images (A = anterior; P = posterior; S = superior; I = inferior). Invasive tumour is digitally contoured in green. The cyan boxes represent areas which would be sampled in the conventional pathology evaluation, as assessed by the pathology assistant on optical images aided by palpation of tissue slices. There are 14 whole-mount sections in total.