Pretreatment Thrombocytosis as a Prognostic Factor in Metastatic Breast Cancer

Table 2

Multivariate Cox regression analysis of parameters possibly related to overall survival of metastatic breast cancer patients.

Variable	Hazard ratio	95% confidence interval		P value
		Lower limit	Upper limit
Thrombocytosis	1.75	1.01	3.02	0.043
Age	1.02	1.011	1.044	0.0009
ER/PR status	0.50	0.31	0.78	0.0028
Her-2 status	0.93	0.57	1.51	0.77
Grade	1.48	0.98	2.21	0.05
Metastatic at diagnosis	0.82	0.54	1.25	0.36
Site of metastasis (bone only versus other)	0.79	0.48	1.29	0.34
1st metastatic treatment (none or hormonotherapy versus chemotherapy)	1.47	0.92	2.33	0.10