Table 2: Multivariate Cox regression analysis of parameters possibly related to overall survival of metastatic breast cancer patients.

VariableHazard ratio95% confidence intervalP value
Lower limitUpper limit

Thrombocytosis1.751.013.020.043
Age1.021.0111.0440.0009
ER/PR status0.500.310.780.0028
Her-2 status0.930.571.510.77
Grade1.480.982.210.05
Metastatic at diagnosis0.820.541.250.36
Site of metastasis (bone only versus other)0.790.481.290.34
1st metastatic treatment (none or hormonotherapy versus chemotherapy)1.470.922.330.10