Table 3: Multivariate Cox regression analysis of parameters possibly related to progression free survival of metastatic breast cancer patients.

VariableHazard ratio95% confidence intervalP value
Lower limitUpper limit

Thrombocytosis2.001.263.170.0031
Age1.000.99751.0230.21
ER/PR status0.590.380.910.018
Her-2 status1.0270.651.610.90
Grade1.541.062.220.021
Metastatic at diagnosis0.610.420.890.012
Site of metastasis (bone only versus other)0.820.521.300.40
1st metastatic treatment (none or hormonotherapy versus chemotherapy)1.370.872.160.17