Pretreatment Thrombocytosis as a Prognostic Factor in Metastatic Breast Cancer

Table 3

Multivariate Cox regression analysis of parameters possibly related to progression free survival of metastatic breast cancer patients.

Variable	Hazard ratio	95% confidence interval		P value
		Lower limit	Upper limit
Thrombocytosis	2.00	1.26	3.17	0.0031
Age	1.00	0.9975	1.023	0.21
ER/PR status	0.59	0.38	0.91	0.018
Her-2 status	1.027	0.65	1.61	0.90
Grade	1.54	1.06	2.22	0.021
Metastatic at diagnosis	0.61	0.42	0.89	0.012
Site of metastasis (bone only versus other)	0.82	0.52	1.30	0.40
1st metastatic treatment (none or hormonotherapy versus chemotherapy)	1.37	0.87	2.16	0.17