Review Article
Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines
Table 5
PIK3CA, HRAS and KRAS mutation status for SUM cell lines.
| | Cell line | PIK3CA status | HRAS status | KRAS status
| | Gene sequence | Amino acid change | Gene sequence | Amino acid change | Gene sequence | Amino acid change |
| | SUM102PT | 3140A>G | H1047R | wt | None | wt | None | | SUM1315MO2 | wt | None | wt | None | wt | None | | SUM149PT | wt | None | wt | None | wt | None | | SUM159PT | 3140A>T | H1047L | 35G>A | G12D | wt | None | | SUM229PE | wt | None | wt | None | 35G>A | G12D | | SUM185PE | 3140A>T | H1047R | wt |
None | wt | None | | SUM190PT | 3140A>G | H1047R | wt | None | wt | None | | SUM225CWN | wt | None | wt | None | wt | None | | SUM44PE | wt | None | wt | None | wt | None | | SUM52PE | wt | None | wt | None | wt | None |
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Source: [69]; +: normal expression; —: not detectable, nd: not determined, wt: wild type.
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