The Value of Intraoperative Frozen Section Analysis for Margin Status in Breast Conservation Surgery in a Nontertiary Institution

Table 3

Summary of demographic, clinicopathologic, and outcome data comparing those patients with and without reoperation.

Clinicopathologic characteristic	All patients (%)		No reoperation	Reoperation	value
Age in years
Median (range)	48 (28–78)
Mean (SD)	48.8 (9.8)		48.9 (9.9)	48.4 (8.6)	0.91
Mode of presentation
Symptomatic tumours	116	(72)	112	4	0.21
Screen detected lesions	45	(28)	45	0
Tumour size in mm (range)
Median (range)	19.0 (4–97)
Mean (SD)	21.6		19.3 (15.6)	33.3 (16.8)	0.17
Stage at diagnosis					0.32
0	20	(12.4)	19	1
I	67	(41.6)	67
II	55	(34.2)	52	3
III	18	(11.2)	18
IV	1	(0.6)	1
Histological type					0.87
DCIS			19	1
Invasive disease only			56	1
Invasive disease with DCIS			80	2
Other invasive			2	0
Neoadjuvant medical therapy
Yes	23	(14.3)	14	23	0.41
No	138	(85.7)	134	4
Disease extent					0.04
Unifocal	121	(75.2)	120	1
Multiple foci at diagnosis	40	(24.8)	37	3
Recurrence					0.95
Local recurrence	3	(1.9)	2 (1.4%)	0
Distant disease/death	4	(2.5)	2 (1.4%)	0
Median follow-up (months)	45
(range)	(18–63)

SD: standard deviation.
DCIS: ductal carcinoma in situ.