Locoregional and Distant Recurrence Patterns in Young versus Elderly Women Treated for Breast Cancer
Table 3
Univariate analysis of risk factors for distant recurrence-free survival in younger women.
Characteristic
N*
Hazard ratio (95% CI)
HR value
Log-rank value
Receptor status
ER/PR+#
71 (62.28)
0.87 (0.33–2.31)
0.786
0.822
Her2+
11 (9.65)
0.71 (0.11–4.48)
0.716
Triple negative
32 (28.07)
—
Grade
1
14 (12.61)
0.80 (0.19–3.36)
0.766
0.818
2
35 (31.53)
0.82 (0.28–2.35)
0.706
3
62 (55.86)
—
Surgery type
Lumpectomy
69 (55.2)
0.28 (0.11–0.72)
0.008
0.003
Mastectomy
56 (44.8)
—
Adjuvant chemotherapy
No
87 (69.6)
0.40 (0.17–0.93)
0.033
0.027
Yes
38 (30.4)
—
Neoadjuvant chemotherapy
No
41 (32.8)
0.89 (0.35–2.26)
0.812
0.735
Yes
84 (67.2)
—
Detected on mammography
No
103 (88.03)
1.10 (0.29–4.25)
0.888
0.692
14 (11.97)
—
Stage at diagnosis
0/I
25 (21.01)
0.09 (0.00–1.55)
0.097
0.018
II/III
94 (78.99)
—
Nodal status
Positive
41 (32.8)
2.58 (1.12–5.98)
0.027
0.020
Negative
84 (67.2)
—
Postmastectomy radiation
No
16 (28.57)
0.17 (0.03–0.98)
0.048
0.014
Yes
40 (71.43)
—
Postlumpectomy radiation
No
5 (7.25)
1.19 (0.05–26.66)
0.912
0.534
Yes
64 (92.75)
—
Final margin status
Positive
2 (1.63)
1.47 (0.08–27.41)
0.795
0.771
Less than 2 mm
14 (11.38)
0.88 (0.23–3.41)
0.851
Greater than 2 mm
107 (86.99)
—
*Total patients for each characteristic may vary due to incomplete medical records for some patients. #ER/PR+: estrogen receptor/progesterone receptor positive.
