Promoter Methylation Status of Breast Cancer Susceptibility Gene 1 and 17 Beta Hydroxysteroid Dehydrogenase Type 1 Gene in Sporadic Breast Cancer Patients

Table 6

Relation between methylation status of BRCA1 promoter in cancer tissue specimens and normal tissue specimens in 40 sporadic breast cancer patients.

		BRCA1 cancer tissues
		⁢⁢Methylated		⁢⁢Unmethylated		⁢⁢Total		value	OR (95% CI)
		Freq.	(%)	Freq.	(%)	Freq.	%
BRCA1; normal tissues	Methylated	11	(78.6)	3	(21.4)	14	100.0	0.001	12.2 (2.5–58.7)
	Unmethylated	6	(23.1)	20	(76.9)	26	100.0
	Total	17	(42.5)	23	(57.5)	40	100.0

Chi-square test is statistically significant at 95% confidence level.