P-Rex1 Expression in Invasive Breast Cancer in relation to Receptor Status and Distant Metastatic Site

Figure 2

P-Rex1 immunohistochemical expression in primary breast cancers and metastatic sites. (a) Primary ER+ tumor with high expression. (b) Primary HER2+ tumor with high expression. (c) Primary triple-negative tumor with no detectable expression in malignant cells. (d) HER2+ lung metastasis with high expression. (e) ER+/HER2− brain metastasis with high expression. (f) ER+/HER2− bone metastasis with no detectable expression in malignant cells. All images were obtained at 200x magnification.