| | Outcome Variable | Effect in the Variance-Component Analysis | Type of Effect | Mathematical Symbol | Index | Maximum of the Index |
| | Mean ROI Value via Manual Segmentations | Subject | Random | | | | | Observer | Fixed or Random | | | | | Time Point | Fixed or Random | | | | | Repetition | Fixed or Random | | | | | Region of Interest | Fixed | | | | | Interaction Terms | Generally Mixed | | | Based on the Appropriate Model Specification |
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