Research Article

Extending Local Canonical Correlation Analysis to Handle General Linear Contrasts for fMRI Data

Figure 8

Activation maps for the contrast E-C of the memory paradigm using corrected -values ( ). Upper row: activations in the anterior portion of the hippocampal complex; lower row: activations in the posterior and middle cingulate cortex and in the precuneus. Note that GLM-NS and cCCA-RG lead to symmetric (left and right) activation patterns in the hippocampus and parahippocampal gyrus and also to weak and localized activations in the posterior/middle cingulate cortex (see white arrows). Using GLM-GS, strong activation patterns become overly bulgy (see black arrow). Compared to GLM-NS, cCCA-RG yields more activated voxels and better connected activations confined to gray matter.
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