Automated Estimation of Acute Infarct Volume from Noncontrast Head CT Using Image Intensity Inhomogeneity Correction

Figure 1

Illustration of the image processing pipeline. After brain-extraction, the NCCT is passed through IIC to generate the intensity-corrected or “restored” image. The input image is then subtracted from the product image to generate a difference map highlighting areas of reduced radiodensity. After thresholding, the volume of the contralateral hemisphere difference map is subtracted from volume of the ipsilateral hemisphere difference map to yield the infarct volume. An MR diffusion-weighted image of the same case performed the following day is included for reference.