Effect of Age and Diabetes on the Response of Mesenchymal Progenitor Cells to Fibrin Matrices
Figure 3
Effects of fibrin surfaces on young and old human MSC. Isolated MSC from young donors and aged donors were grown on fibrin gels for 7 days, and then 1000 cells were seeded into the CFU assays under osteogenic conditions. The number of ALP-positive colonies (grey) and total colony numbers (black) were calculated for young (a) and aged (c) MSC. Mean sizes of colonies were calculated for young (b) and aged (d) donor MSC. *Denotes a statistically significant difference from the other groups.
