Research Article

Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen

Figure 4

The interaction of type IV collagen and C1-inhibitor assessed by fluorescence spectroscopy. (a) The fluorescence spectra of C1-inhibitor alone (2nd line from top), type IV collagen alone (4th line, at bottom of figure), a mixture of type IV collagen and C1-inhibitor (3rd line from top), and the individual spectra of C1-inhibitor alone and type IV collagen alone added together (1st line at top of figure). (b) An amplified view of the same data at the apex of the peaks (between 295 nm and 355 nm).
212417.fig.004a
(a)
212417.fig.004b
(b)