Research Article
Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties
Table 3
Antifungal activity of chitosan solution and nanoparticles against selected fungi species,
. CS: chitosan; NP: nanoparticles.
| | Sample | | Particle size | Zeta potential | | (mg/mL) | | | | (nm) | (mV) | C. albicans | F. solani | A. niger |
| | Amphotericin B (positive control) | | — | — | 0.002 | 0.02 | 0.002 | | HMW CS solution | | — | — | 3 | 3 | 3 | | LMW CS solution | | | | 3 | 3 | 3 | | TMC solution | | | | — | — | — |
| | LMW | 174 ± 38.47 | +39 ± 8.56 | 0.25 | 1 | — | | CS NP prepared from 1 mg/mL CS | HMW | 210 ± 24.54 | +40 ± 3.16 | 1 | 0.5 | — | | TMC | 433 ± 79.59 | +37 ± 2.75 | — | — | — |
| | LMW | 233 ± 41.38 | +38 ± 1.85 | 0.8572 | 0.8572 | — | | Cs NP prepared from 2 mg/mL CS | HMW | 263 ± 86.44 | +52 ± 6.27 | 0.8572 | 0.8572 | 1.7143 | | TMC | 211 ± 89.26 | +33 ± 4.79 | — | — | — |
| | LMW | 255 ± 42.81 | +48 ± 4.78 | 0.6072 | 1.2143 | — | | Cs NP prepared from 3 mg/mL CS | HMW | 301 ± 72.85 | +54 ± 5.01 | 0.6072 | 1.2143 | 2.4286 | | TMC | 297 ± 64.72 | +37 ± 2.52 | — | — | — |
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