Comparison of Modified Chandler, Roller Pump, and Ball Valve Circulation Models for In Vitro Testing in High Blood Flow Conditions: Application in Thrombogenicity Testing of Different Materials for Vascular Applications

Table 2

Roller pump and Hemobile performed at 40 mL/min blood circulation.

	Baseline	Roller pump	Hemobile
Platelet number (10E9/L)	115±36	70±28	117±32^∗
Bleeding constant (sec)	72±7	108±20	99±21
Aggregation (slope)	18.7±7.1	6.9±3	8.7±4.7
Adhesion (10E6/cm^2)	—	0.75±0.73	0.53±0.45
Hemolysis (gHb/L)	0.07±0.06	0.95±0.51	0.18±0.11^∗∗

^∗𝑃<0.05; ^∗∗𝑃<0.01 compared to roller pump.