Comparison of Modified Chandler, Roller Pump, and Ball Valve Circulation Models for In Vitro Testing in High Blood Flow Conditions: Application in Thrombogenicity Testing of Different Materials for Vascular Applications

Table 3

Activation markers in plasma after Hemobile circulation at 40 mL/min in the presence of different grafts (average ± SD).

	Baseline	ePTFE	PET	Dyneema Purity
TxB2 (pg/mL)	21±14	779±642	964±428	948±246
TAT (μg/mL)	0.7±0.7	73.7±118	147.6±53	90.0±131
elastase (μg/mL)	0.32±0.35	4.36±5.27	3.00±3.01	2.85±2.97
C5b-9 (U/mL)	1.55±2.17	3.31±3.01	3.41±2.82	2.60±2.63
hemolysis (gHb/L)	0,02±0.01	0,14±0.1	0,15±0.11	0,08±0.002

TXB2: thromboxane B2; TAT: thrombin-antithrombin III.