Locally derived skin stem cells may harbor the potential to regenerate skin. Stem cells populations have been identified in various niches throughout the skin, including the epidermal stem cell in the hair follicle bulge, sebaceous glands, and interfollicular epidermis. Dermal stem cells may exist in the dermal papilla or dermal extracellular matrix. Adipose-derived stem cells appear to be intimately associated with the perivascular space.
