A Crosslinked HA-Based Hydrogel Ameliorates Dry Eye Symptoms in Dogs

Table 2

Properties of the three materials tested in this study. The concentration of CMHA-S or HA was determined usin a carbazole assay (𝑛=6). Viscosity and shear moduli are averages of 8 samples.

Property	xCMHA-S	HA2	HA4
CMHA-S or HA conc. (mg/mL)	3.77 ± 0.09	2.50 ± 0.03	4.35 ± 0.06
Viscosity at 0.25 s^−1 (Pa·s)	2.82 ± 0.50	0.09 ± 0.03	0.14 ± 0.03
Viscosity at 2.5 s^−1 (Pa·s)	0.66 ± 0.06	0.17 ± 0.01	0.21 ± 0.01
G ′ at 2.5 Hz (Pa)	4.14 ± 1.23	4.46 ± 1.47	3.25 ± 1.19
G ′′ at 2.5 Hz (Pa)	8.75 ± 1.21	4.37 ± 0.70	6.39 ± 1.80
tan 𝛿 at 0.25 Hz	0.7	2.4	1.6
tan 𝛿 at 5 Hz	2.8	1.2	2.5