Cellular Response to a Novel Fetal Acellular Collagen Matrix: Implications for Tissue Regeneration
Figure 5
Flow cytometric analysis of the immune response to PriMatrix implants. (a) Gating scheme for monocyte, macrophage and T-cell analyses. (b) Quantification of the monocyte, macrophage and T-cell response, demonstrating an initial monocyte response on day 3, which transitions to a macrophage and T-cell dominated response at days 3 and 7. This inflammatory response was completely resolved by day 14, consistent with an adaptive tolerance to the implant. **Significant compared to intact skin and sham implant controls.
