Stabilisation of Collagen Sponges by Glutaraldehyde Vapour Crosslinking

Table 1

Examples of previously reported conditions for GA vapour stabilisation of collagen and gelatine materials.

Substrate	Format	Temperature	% GA	Time	Reference
Collagen; (Limed bovine)	Reconstituted; Fibrils	RT	25%	24 h, 48 h	Kato et al. [19]
Collagen; (Bovine)	Reconstituted; Fibrils	RT	25%	96 h	Law et al. [33]
Collagen; (Bovine)	Film	37°C	8%	Various; 3 h to 72 h	Barbani et al. [20]
Collagen; (Bovine)	Electrospun; mat	RT	(Not stated)	24 h	Matthews et al. [34]
Collagen; (Bovine)	Sponges	RT	25%	4 h, 8 h, 24 h	Lickorish et al. [21]
Collagen; (Bovine)	Reconstituted; Fibrils	RT	25%	Various,; 1 h to 24 h	Rho et al. [35]
Collagen; (Bovine)	Electrospun; mat	RT	25%	24 h	Yang et al. [36]
Bacterial; Collagen	Sponge	RT	20%	18 h	Peng et al. [7]
Collagen; (Bovine)	Electrospun; mat	RT	25%	8 h	Takeda et al. [37]
Gelatine; (Fish skin)	Electrospun; mat	37°C	50 vol%	3 h	Songchotikunpan et al. [22]
Gelatine	Electrospun; mat		0.5%	19 h	Sisson et al. [38]
Gelatine; (Porcine)	Electrospun; mat	37°C	“Saturated”	5 min	Dheraprasart et al. [39]
Gelatine; (A-type, B-type)	DHT-treated; Electrospun; mat	4°C	0.06% in acetone/HCl	48 h	Ratanavaraporn et al. [40]
Gelatine; (A-type)	Electrospun; mat	RT	1.5% in EtOH	48 h	Zha et al. [23]
Gelatine; (Fish skin)	Electrospun; mat	40°C	5%	Various,; 0.5 h to 24 h	Gomes et al. [24]
Gelatine; (Fish skin)	Electrospun; mat	40°C	5%	5 h	Gomes et al. [41]

RT: Room temperature.