Strain and Vibration in Mesenchymal Stem Cells

Table 2

Effect of cyclic tensile strain on MSCs seeded on 2D scaffolds.

Scaffold		Cell	Strain (%)	Time (hrs)	Differentiation	Ref.
2D; Natural	Collagen	hMSCs	5	24	Myogenic	[19]
		hMSCs	10	24	Myogenic	[20]
		hMSCs	3, 10	8, 48	Tenogenic (10%)	[21]
		hMSCs	0.8, 5, 10, 15	48	Osteogenesis (<5%); Osteogenic inhibition (>5%)	[22]
2D; Natural + synthetic	Elastin	hMSCs	10	24	Myogenic	[20]
	Silicone	rMSCs	10	N/A	Tenogenic	[23]
	Elastin-silicone	rMSCs	5, 10, 15, 20	24	Myogenic (10%)	[24]
	Elastin-silicone	rMSCs	10	24, 48, 72	Myogenic	[24]

Myogenic expression transiently increased; expression reduced to basal levels after cell alignment.