Molecular Mechanisms Involved in Mesenchymal Stem Cell Migration to the Site of Acute Myocardial Infarction

Table 1

Characteristics of bone marrow-derived MSC: expression of specific antigens, cytokine receptors and adhesion molecules, as well as production of cytokines and matrix molecules.

Expression on MSC	Designation	Reference
Characteristic cell surface antigens	CD73, CD90, CD105, CD166, STRO-1	[17, 22–24]
Cytokines and growth factors	IL- 1𝛼, IL-1𝛽, IL-6, IL-7, IL-8, IL-11, IL-12, IL-14, and IL-15 LIF, SCF, Flt-3 ligand, GM-CSF, G-CSF, M-CSF, VEGF	[17, 25]
Cytokine receptors and growth factor receptors	IL-1R (CD121), IL-2R (CD25), IL-3R (CD123), IL-4R (CD124), IL-6R (CD126), IL-7R (CD127), LIFR, SCFR, G-CSFR, IFN𝛾R, TNFIR, TNFIIR, TGF𝛽IR, TGF𝛽IIR, bFGFR, PDGFR, EGFR	[10, 22, 26, 27]
Adhesion	Integrins: 𝛼1, 𝛼2, 𝛼3, 𝛼4, 𝛼5, 𝛼v, 𝛽1, 𝛽3, 𝛽4, ICAM-1 (CD54), ICAM-2 (CD102), VCAM-1 (CD106), ALCAM-1 (CD166), LFA-3 (CD58), L-selectin (CD62L), endoglin (CD105), CD44, VLA-4	[10, 22, 28, 29]